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The IAEA assists its Member States in their efforts to develop effective, evidence-based interventions to combat malnutrition in all its forms by nuclear techniques. This publication was developed as an integral part of the IAEAs efforts to contribute to the transfer of technology and knowledge in the application of a widely used nuclear technique in nutrition, i.e. Dual-Energy X-ray Absorptiometry (DXA). It provides information on the theoretical background as well as the practical application of DXA to measure bone mineral density and to assess body composition.