Dynamic Force Spectroscopy and Biomolecular Recognition
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Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. This book covers the most recent ideas and advances in the field of DFS applied to biorecognition. Leading experts in the field offer their perspectives on such important topics as atomic force microscopy, force spectroscopy, interaction geometries, and immobilization strategies.…mehr

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Produktbeschreibung
Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. This book covers the most recent ideas and advances in the field of DFS applied to biorecognition. Leading experts in the field offer their perspectives on such important topics as atomic force microscopy, force spectroscopy, interaction geometries, and immobilization strategies.
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Autorenporträt
Anna Rita Bizzarri received her degree in Physics in 1987 from the University of Rome. She obtained the Ph.D. in Biophysics in 1992 from SISSA in Trieste. After postdoctoral fellowships in Perugia and Mainz she joined the Science Faculty at Tuscia University, Italy, as research assistant. In 2000, she became Associate Professor of Physics and in 2006 she got the position of full Professor. Her scientific interests include spectroscopic investigations and MD simulations of electron transfer metalloproteins. More recently, she has focused on single-molecule level detection by surface enhanced Raman spectroscopy and scanning probe microscopies for both fundamental and applicative aims. Salvatore Cannistraro obtained his degree in Physics in 1972 from Pisa University. He received his Ph.D. in Biophysics at Liegi University,Belgium. In 1977, he became reader of Biophysics at Calabria University. He moved to Perugia University in 1981 as Associate Professor of Molecular Physics. Since 1991, he has been a full professor of Physics, Biophysics, and Nanoscience at Tuscia University, leading the Biophysics and Nanoscience Centre. His scientific interests include optical, magnetic, neutron spectroscopies and modelling of amorphous and biological systems. More recently, he is focusing his activity on the application of AFM, STM, and Raman SERS to single biomolecule detection and nanobiomedicine.