Cholera is a diarrhoeal disease that claims victims during epidemics and remains a public health problem worldwide in general and in the DRC in particular in the FIZI health zone where the disease is endemic. This is a descriptive study of 4618 patients who attended the Fizi CTC from 2010 to 2013. We drew up their eco-epidemiological profile and the data collected were analysed using SPSS and Excel OFFICE 10 software, which enabled us to categorise the patients according to well-defined variables. Results: A total of 4618 cases were admitted, with Baraka being the most common health zone with 1646 cases. The age group most affected was 6-14 years. Compared with occupations, farmers were the most affected. Symptoms mostly appeared within 24 hours, with severe dehydration. Fortunately, the majority of patients recovered. This study has shown that the Fizi health zone, with its multiple armed conflicts favouring promiscuity, poor hygiene and massive population movements, is still a sanctuary for cholera.