D. James Morré, Dorothy M. Morré

ECTO-NOX Proteins

Growth, Cancer, and Aging

• Broschiertes Buch

Produktbeschreibung

This volume documents this unique family of cell surface proteins. Despite masquerading as intractable and difficult to clone and characterize, ENOX proteins have and continue to offer remarkable opportunities for research, commercial development and outside confirmation of therapeutic, diagnostic and new paradigms to help explain complex biological processes.

Produktdetails

• Verlag: Springer / Springer New York / Springer, Berlin
• Artikelnr. des Verlages: 978-1-4899-8845-4
• 2013
• Seitenzahl: 524
• Erscheinungstermin: 20. September 2014
• Englisch
• Abmessung: 235mm x 155mm x 29mm
• Gewicht: 795g
• ISBN-13: 9781489988454
• ISBN-10: 1489988459
• Artikelnr.: 41533032

Inhaltsangabe

Preface.- The ECTO-NOX protein family.- Measurement of ECTO-NOX (ENOX) activities.- The constitutive ENOX1 (CNOX).- Role in plasma membrane electron transport.- Role in the enlargement phase of cell growth.- Role as ultradian oscillators of the cells' biological clock.- Other potential functional roles of ENOX proteins.- ENOX2 (tNOX) and cancer.- Age-related ENOX proteins (arNOX).- The auxin-stimulated ENOX and auxin-stimulation of plant growth.- Cancer therapeutic applications of ENOX2 proteins.- Diagnostic applicastions of ENOX2 proteins.- Appendix A Epilogue: Remaining challenges.- Appendix B Detailed description of 2-D gel electrophoresis western blot early detection protocol.