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Diabetes mellitus especially type II has recently become a serious disease with the high possibility of an increased rate of comorbidity since it is a long-life disease that requires a person with adequate knowledge regarding the disease itself as well as good self-care. This study aims to evaluate the effectiveness of an educational program on the knowledge and self-care of patients with type II diabetes mellitus. The study was conducted From November 27th, 2020 to March 1th 2022.