The purpose is to observe the performance of the use of educational software in the learning process, specifically in the area of human anatomy, and its relationship with the creation of technological and pedagogical tools that facilitated the study method. Through a quasi-experimental design, the research was applied to a population made up of students enrolled in the Nursing course in the 2017 academic year - in the anatomy I course, which corresponds to the first year of the study plan. For this purpose, two divisions were taken as a sample, representing a total of 54 students, 26 from group I and 28 from group II. Of these, some names were removed due to non-attendance and because they were irregular students, leaving 20 from group I, which was the control group, and 20 from group II, the experimental one. The experimental group received the bonelab software support classes for the study of the bones in 3D. Those in the control group received classes using the traditional method.