Over the years, there has been scientific researches to minimize the health hazards potentiated by some toxins done on phyto-chemicals extracted from plant. However, paucity of scientifically proven healing results and spread of findings on some medicinal plants remains a challenge. Efforts to stem the contraindications of some of these synthesized drugs using plant medicine (phyto-medicine) as alternatives in many parts of Africa and the rest of the world has been accelerated.Fruits and vegetables have been recognized as natural sources of various bioactive compounds. The bioactive properties of fruits and vegetables could be attributed to their phyto chemical constituents .One of such vegetable plants is Sesame indicum. Sesame seeds are reported to be rich in phyto estrogenic lignans. Sesame seeds oil has been used as healing oil for thousands of years, it naturally possess antibacterial properties. It also possesses anti-fungal, antiviral and anti-inflammatoryeffects. This book seeks to disseminate evidenced based scientific research on medicinal plants and could be especially useful to research students of sciences, pharmaceutical sciences, medicine and the general public.