This work revealed the destructive effects of sublethel doses of 4-nonylphenol on the heamatological parameters, biochemical variables and hormonal activity of the adults African Catfish, Clarias gariepinus. Also, histopathological and ultrastructure studies of some organs using TEM confirmed these effects. These destructive effects were studied on the early developmental stages in terms of incubation time, fertilization rate, hatching rate, mortality rate, morphological malformations and histopathological changes using SEM. The genotoxicity of this pollutant was studied using SDS-PAGE, RAPD-PCR, apoptosis detection and micronucleus test.
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