Katty Alcívar Zambrano

Effects of ACE inhibitors and Beta-blockers in Cancer Prevention

Effectiveness of IECAS and BB for the Prevention of Cardiotoxicity Produced by Chemotherapeutics and Tretazumab in Cancer

• Broschiertes Buch

Produktbeschreibung

Survival of cancer patients has improved as a result of the beneficial effect of chemotherapy and monoclonal antibodies directed against human epidermal growth factor receptor 2 such as trastuzumab. The treatments, however, are accompanied by known cardiotoxic effects, which in some may be mild and asymptomatic but in their most severe forms can lead to heart failure which seriously worsens the prognosis. Several cancer treatments have been associated with the potential risk of cardiotoxicity, including: anthracyclines, 5-fluorouracil, cyclophosphamide, tyrosine kinase inhibitors, vascular endothelial growth factor, immune checkpoint inhibitors, HER-2 antagonists, as well as radiotherapy. Most of the published data on cardiotoxicity, however, are focused on anthracyclines and trastuzumab. This paper will discuss the usefulness of beta-blockers alone and in combination therapy with converting enzyme inhibitors (ACE inhibitors) for the prevention of cardiotoxicity in cancer patients treated with anthracyclines and trastuzumab.

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Produktdetails

• Verlag: Our Knowledge Publishing
• Seitenzahl: 52
• Erscheinungstermin: 11. Juli 2023
• Englisch
• Abmessung: 220mm x 150mm x 4mm
• Gewicht: 96g
• ISBN-13: 9786206229360
• ISBN-10: 620622936X
• Artikelnr.: 68399271

Autorenporträt

Clinical Cardiology "Interamerican Open University" Buenos Aires- ArgentinaDiploma Echocardiography and cardiac doppler (egama) - ArgentinaSurgeon "Eloy Alfaro de Manabi Secular University" - Ecuador