HIV/AIDS is a problematic issue in most countries across the world.Most countries have made efforts to combat the Pandemic in line with Millennium Development Goal NO. 6.The book analyzes HIV/AIDS awareness levels in the sugar factory,correlation analysis between HIV/AIDS and factory output/sales turnover/profits. The Cobb Douglas production function was applied to analyze data which makes this book unique and useful for Economic policy analysts,Health economists and government agencies dealing with HIV/AIDS.Factors responsible for high prevalence and Incidence of HIV/AIDS in chemelil sugar factory were addressed. This book will be useful also for students both at under and post graduate levels , Health Researchers,policy makers across sectors.