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Lead is one of the most toxic environmental contaminants for humans and other animals. Its harmful effects can affect the functioning of all organs and systems and depend on the plasma levels of this metal. Currently, a blood concentration of approximately 60mig/dL is considered safe. However, studies have shown that plasma values below this biological tolerance index generate deleterious effects on the body. Therefore, the aim of this study was to evaluate the effects of acute administration of a low concentration of lead on kidney function.