Effects of MDMA on the human body
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The effects of MDMA (3,4-methylenedioxy-N-methylamphetamine, commonly known as "ecstasy") on the human brain and body are complex, interacting with several neurochemical systems. It induces serotonin, dopamine, norepinephrine, and acetylcholine release, and can act directly on a number of receptors, including a2-adrenergic (adrenaline) and 5HT2A(serotonin) receptors. MDMA promotes the release of several hormones including prolactin, oxytocin, ACTH, dehydroepiandrosterone (DHEA), and the antidiuretic hormone vasopressin (which may be important in its occasional production of water intoxication…mehr

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Produktbeschreibung
The effects of MDMA (3,4-methylenedioxy-N-methylamphetamine, commonly known as "ecstasy") on the human brain and body are complex, interacting with several neurochemical systems. It induces serotonin, dopamine, norepinephrine, and acetylcholine release, and can act directly on a number of receptors, including a2-adrenergic (adrenaline) and 5HT2A(serotonin) receptors. MDMA promotes the release of several hormones including prolactin, oxytocin, ACTH, dehydroepiandrosterone (DHEA), and the antidiuretic hormone vasopressin (which may be important in its occasional production of water intoxication or hyponatremia). It's not fully understood why MDMA induces these unusual psychoactive effects. Most explanations focus on serotonin release. MDMA causes serotonin vesicles in the neurons to release quantities of serotonin into the synapses. From studies using pretreatment with an SSRI to block the ability of MDMA to release serotonin in volunteers, we know that serotonin release is necessary for most effects of MDMA in humans. Released serotonin is believed to stimulate several receptors that contribute to the experiential effects of MDMA.