"Protective effects of phyllanthus niruri Nanoparticles on Diabetic nephropathy in drug induced diabetic Rodents" in that by using the phyllanthus niruri plant extract we prepare Nanoparticles for treatment of diabetic nephropathy.Now a days diabetic nephropathy is a major cause for death and to reduce the nephropathy due to diabetic patients used herbal medicine,day to day treatment we used standard drug but herbal drug treatment is less toxic and more effective.With the help of animals (Rodents) experience are performed.Phyllanthus Niruri extract prepared and then from that extract we prepare Silver Nanoparticles and then adjust the dose according to animals body weight and carry out the experiment.