Effects of Purslane Ethanolic extract on doxorubicin-induced toxicity
Biochemical effects of Purslane Ethanolic extract on doxorubicin-induced toxicity in albino rats
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Doxorubicin (DOX), an anthracycline antibiotic, is a broad-spectrum antineoplastic agent, which is commonly used in the treatment of uterine, ovarian, breast and lung cancers, Hodgkin's disease and soft tissue sarcomas as well as in several other cancer types. The effect of doxorubicin intraperitoneal injection at dose level of 4 mg/kg b.w./week without or with oral administration of ethanolic purslane (Portulaca oleracea) shoot (leaves and stems) extract (50 mg/kg b.w./ day) or seed extract (50 mg/kg b.w.day) for 6 weeks was evaluated in adult male rats.
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