Hepatocellular carcinoma (HCC) is currently the fifth most common solid tumor worldwide and the third leading cause of cancer-related death. Percutaneous ethanol injection (PEI) and radio frequency ablation (RFA) techniques became well-known procedures for controlling small HCC. Inflammation is a major contributing factor to carcinogenesis specially HCC. Inflammatory mediators including interleukin- 6 (IL-6) and neutrophil to lymphocyte ratio (NLR) are good candidates to stimulate tumor growth and progression.
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