Online learning alternatives are growing rapidly in Vietnam. Recently many education institutions have offered online English courses. It is increasingly recognized in education research to find out what learners think about online learning and what makes them successful in an online learning environment. Educators should better understand learners' perceptions of interaction and their attitudes towards learning English online. This research examines the students' perceptions of interaction and attitudes towards learning online to provide information that may assist education institutes and teachers in meeting students' needs and improving students' performance.