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This comprehensive book addresses the acute emergencies in neuromuscular disease from a novel perspective, focusing on clinical management and treatment of these disorders rather than the more traditional neuropathology, neurogenetics, and neurophysiology approaches. The book fills the gap in guidelines by providing an evidence-based guidance for the clinical adult or pediatric neurologist confronted by an acutely ill patient in a potentially life-threatening situation.
The book is structured according to pathophysiological principles, but each chapter is strictly organised around case
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Produktbeschreibung
This comprehensive book addresses the acute emergencies in neuromuscular disease from a novel perspective, focusing on clinical management and treatment of these disorders rather than the more traditional neuropathology, neurogenetics, and neurophysiology approaches. The book fills the gap in guidelines by providing an evidence-based guidance for the clinical adult or pediatric neurologist confronted by an acutely ill patient in a potentially life-threatening situation.

The book is structured according to pathophysiological principles, but each chapter is strictly organised around case vignettes that emphasize clinical relevance allowing the non-specialist to access complex scientific backgrounds. The electronic supplementary material and multimedia are provided as an integral tool to facilitate accessibility and understanding of a notoriously difficult field of neurology. Finally, the role of patients, who are increasingly involved in many management decisions, is highlighted in a chapter on ethical issues discussing withholding or withdrawing life-sustaining therapy, patient end-of-life values, wishes and preferences, and on advanced directives.

The publication is aimed equally at the non-specialist neurologist in frontline clinical practice confronted by a rare disorder needing immediate management decisions, at the clinical specialist referring for guidance in specific management aspects, and at the specialist researcher keen to maintain clinic relevance.

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Autorenporträt
Maxwell Damian trained in Germany and the UK, and specialises in genetic muscle disease and in neurocritical care. He was consultant and director of the neurological ICU in the universities of Giessen and Dresden, Germany, before continuing work in the UK, specialising in critical care aspects of neuromuscular disease and in research on hypoxic brain injury. He has been co-chair of the Neurocritical Care scientific panel of the European Academy of Neurology, 2015-2020; chair of the specialist group in Neurocritical Care of the Association of British Neurologists; chair of the accreditation committee of the Neurocritical Care Society, USA. He retired from Cambridge University Hospitals in 2020 but continues research work at the University Department of Anaesthetics, Cambridge University and at the Essex Cardiothoracic Centre, UK.   Marianne de Visser is an adult neurologist at the Amsterdam University Medical Centers,  location AcademicMedical Center in Amsterdam, The Netherlands and emeritus Professor of Neuromuscular Diseases. She was trained at the University Hospital of Amsterdam. In 1988 she was a visiting scientist at Dr. Andrew Engel's lab at Mayo Clinic, Rochester, Minnesota where she performed ultrastructural studies on skeletal muscle in dermatomyositis. She obtained a position at the Department of Neurology of the Academic Medical Center in Amsterdam and was appointed as Professor of Neuromuscular Diseases at the University of Amsterdam in 1993. Her research interests are rare neuromuscular disorders such as myositis, hereditary neuropathies, postpolio syndrome and motor neuron disorders. Her work on ALS kindled interest in palliative care. She was a member of the Governing Board of the European Academy of Neurology (EAN), first as Treasurer and subsequently as Secretary-General (2014-2020). She also served on the Management Committee of the World Federation of Neurology (Elected Trustee (2002-2008), Co-opted Trustee (2020-2021)). She was co-chair of the EAN Scientific Panel on Rare Neurological Diseases (2020-2022) and now member of the Management Group.