With more than 40 contributions from expert authors, this is an extensive overview of all important research topics in the field of bioengineering, including metabolic engineering, biotransformations and biomedical applications.Alongside several chapters dealing with biotransformations and biocatalysis, a whole section is devoted to biofuels and the utilization of biomass. Current perspectives on synthetic biology and metabolic engineering approaches are presented, involving such example organisms as Escherichia coli and Corynebacterium glutamicum, while a further section covers topics in…mehr
With more than 40 contributions from expert authors, this is an extensive overview of all important research topics in the field of bioengineering, including metabolic engineering, biotransformations and biomedical applications.Alongside several chapters dealing with biotransformations and biocatalysis, a whole section is devoted to biofuels and the utilization of biomass. Current perspectives on synthetic biology and metabolic engineering approaches are presented, involving such example organisms as Escherichia coli and Corynebacterium glutamicum, while a further section covers topics in biomedical engineering including drug delivery systems and biopharmaceuticals. The book concludes with chapters on computer-aided bioprocess engineering and systems biology. This is a part of the Advanced Biotechnology book series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question. Invaluable reading for biotechnologists and bioengineers, as well as those working in the chemical and pharmaceutical industries.Advanced BiotechnologyBiotechnology is a broad, interdisciplinary field of science, combining biological sciences and relevant engineering disciplines, that is becoming increasingly important as it benefits the environment and society as a whole. Recent years have seen substantial advances in all areas of biotechnology, resulting in the emergence of brand new fields. To reflect this progress, Sang-Yup Lee (KAIST, South Korea), Jens Nielsen (Chalmers University, Sweden), and Gregory Stephanopoulos (MIT, USA) have joined forces as the editors of a new Wiley-VCH book series. Advanced Biotechnology will cover all pertinent aspects of the field and each volume will be prepared by eminent scientists who are experts on the topic in question.
Ho Nam Chang is Professor Emeritus at the Department of Chemical and Biomolecular Engineering at the Korea Advanced Institute of Science and Technology (KAIST). He studied at Seoul National University (South Korea) and received his Master and Ph.D. degrees from Stanford University (USA) in 1971 and 1975. After this time, he returned to Korea and became Professor at KAIST, a position he hold until his retirement in 2010. In 1990, he was elected Director of the Bioprocess Engineering Research Center at KAIST. During his scientific career, Ho Nam Chang became a Humboldt Fellow at the University of Erlangen (Germany, 1980 to 1981), President of the Korean Society for Biotechnology and Bioengineering (1994 to 1995), Member of the Presidential Council on Science and Technology of Korea (1995 to 1997) and Honorary Professor at Nanjng University of Technology (China).Jens Nielsen has a PhD degree (1989) in Biochemical Engineering from the Danish Technical University (DTU), and after thatestablished his independent research group and was appointed full Professor there in 1998. He was Fulbright visiting professor at MIT in 1995-1996. At DTU he founded and directed the Center for Microbial Biotechnology. In 2008 he was recruited as Professor and Director to Chalmers University of Technology, Sweden. Jens Nielsen has received numerous Danish and international awards including the Nature Mentor Award, and is member of several academies, including the National Academy of Engineering in USA and the Royal Swedish Academy of Science. He is a founding president of the International Metabolic Engineering Society.Professor Gregory Stephanopoulos is the W. H. Dow Professor of Chemical Engineering at the Massachusetts Institute of Technology (MIT, USA) and Director of the MIT Metabolic Engineering Laboratory. He is also Instructor of Bioengineering at Harvard Medical School (since 1997). He has been recognized by numerous awards from the American Institute of Chemical Engineer
s (AIChE) (Wilhelm, Walker and Founders awards), American Chemical Society (ACS), Society of industrial Microbiology (SIM), BIO (Washington Carver Award), the John Fritz Medal of the American Association of Engineering Societies, and others. In 2003 he was elected member of the National Academy of Engineering (USA) and in 2014 President of AIChE.
Inhaltsangabe
Part I1. Mass Production of Full-Length lgG Monoclonal Antibodies from Mammalian, Yeast, and Bacterial Hosts2. Volatile Fatty Acids Platform: Concept and Application3. Separation of Butanol, Acetone and Ethanol4. Bacterial Biofertilizers: High Density CultivationsPart II5. Overview of Microalgae-Based Carbon Capture and Utilization6. Bioengineering of Microbial Fuel Cells: From Extracellular Electron Transfer Pathway to Electroactive BiofilmPart III 7. Noninvasive Optical Imaging Techniques in Clinical Application8. Advanced Short Tandem Repeat Genotyping for Forensic Human Identification9. Bioelectronic Nose10. Advanced Applications of Nano-Scale Measuring Systems for Biosensors11. DNA Microarray-Based Technologies to Genotype Single Nucleotide Polymorphisms12. Advanced Genetic Engineering of Microbial Cells for Biosensing Applications13. Biosynthesis and Applications of Silver NanoparticlesPart IV 14. Enzymatic Reactions in Ionic Liquids15. Whole-Cell Biocatalysts using Enzymes Displayed on Yeast Cell Surface16. Production of Valuable Phenolic Compounds from Lignin by Biocatalysis: State of the Art Perspective17. Enzyme Immobilization on Nanoparticles: Recent Applications18. Over-Expression of Functionally Active Inclusion Bodies of Enzymes in Recombinant Escherichia coli19. Design of Artificial Supramolecular Protein Assemblies by Enzymatic Bioconjugation for Biocatalytic ReactionsPart V 20. Gasification Technologies for Lignocellulosic Biomass21. Biological Pretreatment of Lignocellulosic Biomass for Volatile Fatty Acid Production22. Potential Lignocellulosic Biomass Resources in ASEAN Countries23. Biopolymers Based on Raw Materials from Biomass24. Biofuels, Bio-Power, and Bio-Products from Sustainable Biomass: Coupling Energy Crops and Waste with Clean Energy TechnologiesPart VI 25. Recent advances in mass spectrometry-based proteomic methods for discovery of protein biomarkers for complex human diseases26. Genome Editing Tools for Escherichia coli and their Application in Metabolic Engineering and Synthetic Biology27. Metabolic Engineering of Microorganisms for the Production of Lactate-Containing Polyesters28. Metabolic Engineering of Solventogenic Clostridia for Butanol Production29. Synthetic Biology for Corynebacterium glutamicum, and Industrial Host for White BiotechnologyPart VII30. Current Research in Korean Herbal Cosmetics31. Mussel-Mimetic Biomaterials for Tissue Engineering ApplicationsPart VIII32. Application of Lactic Acid Bacteria for Food Biotechnology33. Microbial Lipid Production from Volatile Fatty Acids by Oleagionus Yeast34. Microbial Metabolic Engineering for Production of Food IngredientPart IX35. Controlled Delivery Systems of Protein and Peptide Therapeutics36. Cell Delivery Systems using Biomaterials37. Bioengineered Cell-Derived Vesicles as Drug-Delivery Carriers38. Smart Drug Delivery Devices and Implants39. Advanced Genetic Fusion Techniques for Improving the Pharmacokinetic Properties of BiologicsPart X40. Metabolism combined growth model construction and its application to optimal bioreactor operation41. Software Applications for Phenotype Analysis and Strain Design of Cellular Systems42. Metabolic Network Modeling for Computer-Aided Design of Microbial Interactions43. Bioprocess Simulation and Scheduling44. Overview on Bioprocess Simulation
Part I1. Mass Production of Full-Length lgG Monoclonal Antibodies from Mammalian, Yeast, and Bacterial Hosts2. Volatile Fatty Acids Platform: Concept and Application3. Separation of Butanol, Acetone and Ethanol4. Bacterial Biofertilizers: High Density CultivationsPart II5. Overview of Microalgae-Based Carbon Capture and Utilization6. Bioengineering of Microbial Fuel Cells: From Extracellular Electron Transfer Pathway to Electroactive BiofilmPart III 7. Noninvasive Optical Imaging Techniques in Clinical Application8. Advanced Short Tandem Repeat Genotyping for Forensic Human Identification9. Bioelectronic Nose10. Advanced Applications of Nano-Scale Measuring Systems for Biosensors11. DNA Microarray-Based Technologies to Genotype Single Nucleotide Polymorphisms12. Advanced Genetic Engineering of Microbial Cells for Biosensing Applications13. Biosynthesis and Applications of Silver NanoparticlesPart IV 14. Enzymatic Reactions in Ionic Liquids15. Whole-Cell Biocatalysts using Enzymes Displayed on Yeast Cell Surface16. Production of Valuable Phenolic Compounds from Lignin by Biocatalysis: State of the Art Perspective17. Enzyme Immobilization on Nanoparticles: Recent Applications18. Over-Expression of Functionally Active Inclusion Bodies of Enzymes in Recombinant Escherichia coli19. Design of Artificial Supramolecular Protein Assemblies by Enzymatic Bioconjugation for Biocatalytic ReactionsPart V 20. Gasification Technologies for Lignocellulosic Biomass21. Biological Pretreatment of Lignocellulosic Biomass for Volatile Fatty Acid Production22. Potential Lignocellulosic Biomass Resources in ASEAN Countries23. Biopolymers Based on Raw Materials from Biomass24. Biofuels, Bio-Power, and Bio-Products from Sustainable Biomass: Coupling Energy Crops and Waste with Clean Energy TechnologiesPart VI 25. Recent advances in mass spectrometry-based proteomic methods for discovery of protein biomarkers for complex human diseases26. Genome Editing Tools for Escherichia coli and their Application in Metabolic Engineering and Synthetic Biology27. Metabolic Engineering of Microorganisms for the Production of Lactate-Containing Polyesters28. Metabolic Engineering of Solventogenic Clostridia for Butanol Production29. Synthetic Biology for Corynebacterium glutamicum, and Industrial Host for White BiotechnologyPart VII30. Current Research in Korean Herbal Cosmetics31. Mussel-Mimetic Biomaterials for Tissue Engineering ApplicationsPart VIII32. Application of Lactic Acid Bacteria for Food Biotechnology33. Microbial Lipid Production from Volatile Fatty Acids by Oleagionus Yeast34. Microbial Metabolic Engineering for Production of Food IngredientPart IX35. Controlled Delivery Systems of Protein and Peptide Therapeutics36. Cell Delivery Systems using Biomaterials37. Bioengineered Cell-Derived Vesicles as Drug-Delivery Carriers38. Smart Drug Delivery Devices and Implants39. Advanced Genetic Fusion Techniques for Improving the Pharmacokinetic Properties of BiologicsPart X40. Metabolism combined growth model construction and its application to optimal bioreactor operation41. Software Applications for Phenotype Analysis and Strain Design of Cellular Systems42. Metabolic Network Modeling for Computer-Aided Design of Microbial Interactions43. Bioprocess Simulation and Scheduling44. Overview on Bioprocess Simulation
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