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This book provides an overview of current knowledge and discusses some of the unanswered questions at the forefront of the research in cancer management. Cancer is now the most frequent reason of death in the world. Nowadays, because of early identification, improved handling and superior life expectancy, a lot of cancer patients normally live a long and healthy life. This book presents recent advances in diagnosis and treatment of precise cancers. Evidence based approaches in the selection of cancer treatment and significant laboratory advancements can be used to identify new protein biomarkers of cancers in diagnosis and to estimate the precision of the treatment.