Systemic medical condition affects the routine dental procedures. A good number of the adult and geriatric patients may invariably be medically compromised, the incidence might be slightly lesser among young patient Medical conditions which may be hidden and without symptoms are detected only on elaborate investigations. Such conditions may adversely affect the patients and is a concern for dental practitioners causing unexpected problems. Therefore, a thorough evaluation of the medical conditions of the patient is the first priority in the management of medically complex cases. This book focuses on a number of medical problems that dental professionals might encounter, which necessitate care to prevent potential complications. These include hypertension, ischemic heart disease, cardiac arrhythmia, liver disease, allergy, acquired immune deficiency syndrome, organ transplantation and diabetes mellitus.