Endometrial aspiration was carried out as an outpatient procedure in 100 cases presenting with various gynecological problems with Karman s cannula followed by dilatation and curettage for histopathologic correlation Age group of the patients in the present study ranged from 20-60yrs with mean age of 45yrs. The commonest mode of presentation was menorrhagia. The adequacy of the samples for cytology was 92%. Aspiration cytology findings were compared with histopathology sections. Among 100 cases studied, proliferative phase were 50 cases, secretory phase- 25 cases, endometrial hyperplasia -7 cases, endometritis-3 cases, of which 1 case was tubercular endometritis, 2 cases of proliferative and secretory pattern and 2 cases of malignancies. The diagnostic accuracy of endometrial aspirates was 100% for malignancies, endometritis and atypical hyperplasias and 92% for secretory phase, 88% for proliferative phase and 60% for simple hyperplasia. In the present study the over all diagnostic accuracy of adequate samples was 87.7%. Aspiration cytology was more reliable in diagnosing malignant lesions than benign lesions of endometrium.