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Optical coherence tomography (OCT) is a
noninvasive, noncontact imaging modality that uses
coherent gating to obtain high-resolution
cross-sectional images of tissue microstructure.
This book focuses on endoscopic OCT diagnosis.
Because of high-resolution ability of OCT technology,
its endoscopic diagnosis aims to perform optical
biopsy without damaging the tissue, detect early
stage diseases and monitor the healing effect after
surgery. The organs such as human vessel, vocal
cord, gastrointestinal track and airway are
investigated. In order to access these organs, four
OCT endoscopes are designed to deliver infrared light
to the region of interest.
Additionally, a second harmonic spectrometer based
OCT is designed to increase OCT image contrast. With
the contrast enhancement from second harmonic
generation, the structure of highly organized tissue,
like collagen, is obtained. This information is
complementary to the standard OCT. Second harmonic
OCT has the potential to provide molecular contrast
for in vivo clinical application.
noninvasive, noncontact imaging modality that uses
coherent gating to obtain high-resolution
cross-sectional images of tissue microstructure.
This book focuses on endoscopic OCT diagnosis.
Because of high-resolution ability of OCT technology,
its endoscopic diagnosis aims to perform optical
biopsy without damaging the tissue, detect early
stage diseases and monitor the healing effect after
surgery. The organs such as human vessel, vocal
cord, gastrointestinal track and airway are
investigated. In order to access these organs, four
OCT endoscopes are designed to deliver infrared light
to the region of interest.
Additionally, a second harmonic spectrometer based
OCT is designed to increase OCT image contrast. With
the contrast enhancement from second harmonic
generation, the structure of highly organized tissue,
like collagen, is obtained. This information is
complementary to the standard OCT. Second harmonic
OCT has the potential to provide molecular contrast
for in vivo clinical application.