Endothelium

Molecular Aspects of Metabolic Disorders
Herausgeber: Engin, Ayse Basak; Engin, Atilla

• Gebundenes Buch

Produktbeschreibung

The function and life span of endothelial cells have a large impact upon the quality and expectancy of an individual's life. During low perfusion, the adaptation of different cells to hypoxia precipitate the aggressive progression of diseases. Although the clinical studies have convincingly shown that endothelial dysfunction occurs whenever the biological functions or bioavailability of nitric oxide are impaired, in all these scenarios, the role of endothelial cell-destructive process cross-talk is yet poorly understood. This book focuses on the contribution of molecular mechanisms to endothelial dysfunction in related metabolic disorders.

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Produktdetails

• Verlag: Taylor & Francis Ltd (Sales)
• Seitenzahl: 468
• Erscheinungstermin: 29. Mai 2013
• Englisch
• Abmessung: 234mm x 156mm x 25mm
• Gewicht: 830g
• ISBN-13: 9781466582798
• ISBN-10: 1466582790
• Artikelnr.: 37272981

Autorenporträt

Ayse Basak Engin, Atilla Engin

Inhaltsangabe

Physiological importance of endothelium. Vascular fluid mechanics in the
regulation of endothelial function. Ultrastructure of endothelium and
endothelial microparticules. Origin of endothelial progenitor cells and
their functions. Endothelial dysfunction, cytokines and their genetic
variations. Oxidative stress and endothelium: Cellular signaling, nitric
oxide and reactive radicals. Asymmetric dimethylarginine and endothelial
dysfunction. Endothelial Dysfunction and Diabetes Mellitus. Obesity,
metabolic syndrome and endothelium. Vascular endothelium and
renin-angiotensin system. Endothelial dysfunction in chronic kidney disease
patients and renal transplant recipients: Emerging diagnostic and
therapeutic options. Homocysteine and endothelial dysfunction. Oxidative
stress and angiogensisis in tumor progression. Nanoparticle: As a messenger
between environment and endothelium.