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This work conducted for identification of environmental and economic impacts of fish diseases, as well as to investigate the most important fish diseases affecting freshwater fish under conditions and their effect on the economic and productive efficiency of fish production farms. It was provide an overview of some negative effects of fish diseases on environments. Economic losses associated with fish disease have international implications, as aquaculture products are traded internationally. Aquatic pollution is still a problem in many freshwater and marine environments, it causes negative effects for the health of aquatic animals, and there is a clear association between pollution and mortalities.