Arthur R. Schulz, Schulz Arthur R.

Enzyme Kinetics

From Diastase to Multi-Enzyme Systems

• Gebundenes Buch

Produktbeschreibung

This textbook for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady-state enzyme kinetics from the basic principles inherent in the Henri equation to the expressions that describe the control of multi-enzyme pathways. Steady-state kinetic equations are derived with the use of the connection matrix method, and an algorithm is developed that can be implemented easily for computer-based derivation of the equations. Throughout the book emphasis is placed on a proper interpretation of the kinetic behavior of multi-reactant enzymic reactions and on the interpretation of control coefficients in terms of metabolic control. Problems are included at the end of each chapter and their solutions are found at the end of the book.

Produktdetails

• Verlag: Cambridge University Press
• Seitenzahl: 260
• Erscheinungstermin: 9. Juni 2003
• Englisch
• Abmessung: 235mm x 157mm x 20mm
• Gewicht: 579g
• ISBN-13: 9780521445009
• ISBN-10: 0521445000
• Artikelnr.: 21789567

Inhaltsangabe

Preface
Part I. Basic Steady State Enzyme Kinetics: 1. Derivation of a rate equation
2. A closer look at the basic assumptions
3. Enzyme inhibition
4. Reversible enzyme-catalyzed reactions
Part II. Enzyme Reaction Sequence: 5. Multi-reactant enzymic reactions
6. Analysis of multi-reactant enzyme kinetics
7. Prediction of reaction sequence
8. Enzyme-catalyzed isotopic exchange
9. Kinetic isotope effect on steady state parameters
10. The effect of pH on enzyme kinetics
Part III. Non-Hyperbolic Enzyme Kinetics: 11. The causes of non-hyperbolic enzyme kinetics
12. Analysis of non-hyperbolic enzyme kinetics
13. The effect of subunit interactions on enzyme kinetics
Part IV. Control of Multi-Enzyme Systems: 14. Control of linear multi-enzyme systems
15. Control of branched multi-enzyme systems
16. Biochemical systems theory
Part V. Solutions To Problems: Author index
Subject index.