Low back pain is the most common public health problem throughout the world related to Nursing profession. The etiology of low back pain is assumed to be of multi-factorial origin as individual, work-related and psychosocial factors can contribute to its development. The study included 395 Nurses and gave a response rate of 91.9%. The mean age was 30.6 (±8.4) years. Nearly half of the participants (n=181, 45.8%, 95% CI (40.8%- 50.6%)) were complained low back pain. There were statistical significant association between low back pain and working shift, physical activities at work, sleep disturbance and felt little pleasure by doing things. The prevalence of low back pain was found among Nurses. Preventive measures should be taken to reduce the risk of low back pain by educational programs on back care ergonomics and arranging proper rest periods.