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The Epigenetic Keys to Therapeutics Effectiveness of Fluoropyrimidine Therapy in Colorectal Cancer. Global DNA methylation as 5- methyl cytosines could be considered as a prognostic determinant of treatment efficacy. The methylation and expression of cycloxygenase and fluoropyrimidine metabolizing genes exhibited a clinical significance for individualized treatment. The Molecular Follow- Up along with the Clinicopathological Follow- Up is crucial for best management of colorectal cancer.

Produktbeschreibung
The Epigenetic Keys to Therapeutics Effectiveness of Fluoropyrimidine Therapy in Colorectal Cancer. Global DNA methylation as 5- methyl cytosines could be considered as a prognostic determinant of treatment efficacy. The methylation and expression of cycloxygenase and fluoropyrimidine metabolizing genes exhibited a clinical significance for individualized treatment. The Molecular Follow- Up along with the Clinicopathological Follow- Up is crucial for best management of colorectal cancer.
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Autorenporträt
Mariam A. Fouad Hafez, PhD Cancer Biology (Pharmacology and Experimental Oncology), Lecturer in Pharmacology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Egypt.