Epigenetic Regulation of Lymphocyte Development

Herausgegeben:Murre, Cornelis

• Gebundenes Buch

Produktbeschreibung

The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.

Produktdetails

• Current Topics in Microbiology and Immunology 356
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 80023886, 978-3-642-24102-4
• 2012
• Seitenzahl: 204
• Erscheinungstermin: 13. Januar 2012
• Englisch
• Abmessung: 241mm x 160mm x 16mm
• Gewicht: 420g
• ISBN-13: 9783642241024
• ISBN-10: 3642241026
• Artikelnr.: 33867227

Inhaltsangabe

Preface.
Roles of lineage
determining transcription factors in establishing open chromatin
lessons from high
throughput studies.
B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1.
Epigenetic features that regulate IgH locus recombination and expression.
Local and global epigenetic regulation of V(D)J recombination.
Genetic and Epigenetic Regulation of TCRbeta Gene Assembly.
T
cell identity and epigenetic memory.
Encoding stability versus flexibility:  Lessons learned from examining epigenetics in T helper cell differentiation.
The epigenetic landscape of lineage choice: lessons from the heritability of Cd4 and Cd8 expression.
  Subject Index