This book provides insight into Epigenetics; nature vs nurture. It deals with change in gene expression without changing the DNA sequence. Epigenetics includes DNA methylation, Histone Modification and Non coding RNA. Epigentics has a greater influence on medical field like diabetes, cancer and plays an important role in orthodontics (dentistry) to understand the craniofacial deformities as effected by various environmental factors. It has a wide influence in the future of dentistry.