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This issue on Equine Neonatology is guest edited by Pam Wilkins and covers topics such as: Imaging the Equine Neonatal Respiratory Tract: CT and Radiographs; Defining the Systemic Inflammatory Response Syndrome in the Equine Neonate;Ultrasonographic Examination of the Equine Neonate: Thorax and Abdomen;The Equine Neonatal Cardiovascular System in Health and Disease;The Transition From Fetus to Neonate: The Renal System;Sepsis and Septic Shock in the Equine Neonate;The Equine Neonatal Acute Abdomen;Anesthesia of the Equine Neonate in Health and Disease;The Normal and Abnormal Equine Neonatal Musculoskeletal System, and more!