The region of Sindh is positioned atop a fertile land making conditions suitable for farming and irrigation. Being centrally connected to the River Indus has gained an advantage in horticulture and farming over the years. The wide variations in geographical conditions, altitude, soil, climate and culture have created a rich floristic diversity in Sindh. The soil of Sindh land is considered fertile and productive for vegetation. The vegetation of Sindh is naturally beautiful scenic for everyone. Vegetation is also considered part of our literature. Poets and writer always refer the beauty of our nature through the vegetation and green fields of homeland. There are multiple uses of vegetation which are commonly employed by local inhabitants as medicine, fodder and fuel even for agricultural purpose. Since a long time the people of Sindh have used different plants including herbs, shrubs and trees for the treatment of diseases locally. It is investigated that local or traditional medicines are cheaper and easily available for common use. The natural vegetation and greenery is vanishing due to overgrazing of domestic animals, salinity, water-logging and floods.