Basavaraj Nanjwade, Mahesh K. Patel

Ethosomes for Transdermal Delivery

Development of Ethosomal Gel of Curcumin

• Broschiertes Buch

Produktbeschreibung

"Ethosomes are soft malleable vesicles composed mainly of phospholipid, ethanol (relatively high concentration) and water. These soft vesicles represents novel vesicular carrier for enhance delivery to / through skin. The size of ethosome vesicles can be modulated from tens of microns to nanometres. Typically, ethosomes may contain phospholipids with various chemical structures like phosphatidylcholine (PC), hydrogenated PC, phosphatidic acid (PA), phosphatidylserine (PS), phosphatidylethanolamine (PE), phosphatidylglycerol (PPG), phosphatidylinositol (PI), unsaturated PC, alcohol (ethanol or isopropyl alcohol), water and propylene glycol (or other glycols). Such a composition enables delivery of high concentration of active ingredients through skin. Drug delivery can be modulated by altering alcohol: water or alcohol-polyol: water ratio. Some preferred phospholipids are soya phospholipids such as Phospholipon 90 (PL-90). It is usually employed in a range of 0.5-10% w/w. Cholesterol at concentrations ranging between 0.1-1% can also be added to the preparation. Examples of alcohols, which can be used, include ethanol and isopropyl alcohol.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Aufl.
• Seitenzahl: 164
• Englisch
• ISBN-13: 9783847339748
• ISBN-10: 3847339745
• Artikelnr.: 34790009

Autorenporträt

Dr. Basavaraj K. Nanjwade has completed his Ph.D from Rajiv Gandhi University of Health Sciences Karnataka, Bangalore. He is the Director of KLE Society s College of Pharmacy, Nipani, Karnataka, India. He has published 71 papers in reputed national and international journals and 11 Patents. He guided 17 M.Pharm and 7 Ph. D students.