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Litopenaeus vannamaei shrimps are one of the important aqueous proteins resources that has successfully cultured from 1990. Some bacterial diseases like vibriosis among penaeus shrimps have affected shrimp industry. Vibrio harveyi(PTCC1755) and vibrio algynolyticus (MK641453.1) bacteria cause vibriosis in peaeus shrimps. But over use of antibiotics led to the emergence of drug resistant strains of bacteria and nature cause to find and replace natural therapeutic sources like eucalyptus camaldulensis leafs.