E-learning is a complex issue, not only because of its success, but also because of its evaluation. Reliable ways to measure the success and effectiveness of the e-learning systems are required for e-learning applications to be used efficiently. The book aims to provide a prototype to evaluate e-learning systems success and effectiveness. E-learning systems and testing tools used in the study were selected from non-commercial and open source software. For a successful e-learning system assessment, different dimensions of the system, such as standards, quality attributes and several other criteria, should be taken into consideration. In this work, some automated software testing tools were examined and then selected to execute testing of the e-learning systems software. Assessment of e-learning system success was focused on software testing. The whole e-learning process was not considered. It is assumed that performance, accessibility, security, standard compliance and functionality comparisons of the systems can be indicators of the whole e-learning system success. The study should be useful to individuals who deal with e-learning systems effectiveness.