Rohit Mittal, Jimish R. Patel, Rahul Sharma

Evaluation comparison and standardization of arthritis drugs

Evaluate the comparative efficacy of VRP-011 against other standard drugs in arthritis induced rat model

• Broschiertes Buch

Produktbeschreibung

Arthritis is the inflammation of a joint, which can include infiltration of inflammatory cells, synovial hyperplasia, bone erosion and new bone formation, narrowing of the joint space. Arthritis was induced in knee joint cavity of the right hind leg by intra-articular injection of 0.1ml of 1% carrageenan in all groups except control group. Animals are divided into five different groups such as Normal control, arthritis control, Standard A (MOOV) treated group, Standard B (RUMALAYA) treated group and test drug treated group. Catalase activity, Alkaline Phosphatase, MDA and Uric acid were significantly (p 0.001) altered or comes close to the control group in test drug treated group. Paw volume, Knee diameter and body weight were altered in test drug treated group as compare to reference standard A and B. So we concluded that VPR-011 show significant anti-arthritic activity and better efficacy than other reference standard drugs (MOOV) and (RUMALAYA).

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Seitenzahl: 96
• Englisch
• Abmessung: 220mm x 150mm
• ISBN-13: 9783843370295
• ISBN-10: 384337029X
• Artikelnr.: 36833725

Autorenporträt

Mr. Rohit Mittal has obtained his Master of pharmacy degree, Pharmacology in 2010. Since then he has working as Assistant Professor in Surya school of pharmacy, Bapror, Rajpura, District Patiala, Punjab, INDIA. He is the author of several articles published in reputed National and international journals.