Evaluation of a Biomimetic Polymer Nerve Guidance Conduit
David Jay Lee
Broschiertes Buch

Evaluation of a Biomimetic Polymer Nerve Guidance Conduit

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Surgical treatment of peripheral nerve injury clinically remains an unmet medical need as the current gold standard autograft is associated with many drawbacks, including a second surgical procedure, donor site morbidity, mismatch of donor nerve size, and limited donor nerve length. Nerve guidance conduits are a promising alternative to the autograft that promote neuronal growth and guide axonal extension. A nerve guidance conduit was designed using a blend of arginylglycylaspartic acid conjugated polyurea and polycaprolactone containing intraluminal microchannels with aligned nanofibers. The ...