Bangladeshi rural and hilly areas people have long tradition to use various medicinal plants for treating different diseases. Phyto pharmacology is always a vital way for drug discovery. Antibiotic resistance is rising as a challenging threat day by day. Present study was designed to evaluate Analgesic, Antidiarrhoeal and Antibacterial activities of acetone extracts of stem and leaf of Limonia acidissima L. by different methods. Limonia acidissima L. is the family of Rutaceae (Citrus family) which belongs to the monotypic genus Limonia, confined to India, Pakistan, Sri Lanka and Southeast Asia. It is also known as wood apple, elephant-apple, curd fruit, kath bel as well askaitha. The analgesic activity of the samples was studied using acetic acid- induced writhing model in mice. Castor oil-induced antidiarrhealactivity was observed by Thomas method and antimicrobial activity was monitored by disc diffusion method. It is clear that Limonia acidissima L. fruit peels showed significant pharmacological potentiality in different study modelit will be very much possible source for an isolating lead compound for curing the numerous disorders.
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