As a global movement in the disciplines of health sciences, evidence-based care represents a shift in practice - judgment based on scientific evidence overpowering blind adherence to rules. For a specific clinical question, the practice of evidence-based guidelines based on scientific evidence ensures the highest standards of acceptable therapeutic care. Evidence-based dental practice is a systematic approach for obtaining the best available clinically relevant scientific evidence with the ultimate goal and intent of increasing effectiveness and efficacy in clinical decision-making. This book summarizes the principles and scientific methodology to practice evidence-based dentistry through the best utilization of a dentist's experience and clinical expertise and making full use of the most reliable and valid research outcomes.