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The present work is the realization of a research carried out with three transgender people who undertook intentional processes of feminization of the body through different processes. This research, qualitative in nature, implied the objective of describing and analyzing the ways of configuration of personal and affective meaning, the social significance and the interactive implications of such a situation. It is developed from the interpretative analysis thus giving way to the expressive richness of the testimonies and the depth of subjectivity in each of the persons, approaching diverse social meanings in the individual singularity. In this way, the investigative exercise approaches the experiences of such transgender people that involve interventions and transformations in the body and, their words give account of how the personal-affective sense that is at stake in the modification, is produced in the desired construction of the body that appropriates femininity, sitting on its flesh a different reality, opening multiple possibilities, exhibiting alternate sensibilities and filtering other differences.