Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomesin the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medicaldisciplines, as well as their role in cell-cell communication. It is intended to serve as a referencesource for clinicians, physicians, and research scientists who wish to gain insight into the mostrecent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine sinceantibiotics. The discovery of their epigenetic role in intercellular signaling in…mehr
Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomesin the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medicaldisciplines, as well as their role in cell-cell communication. It is intended to serve as a referencesource for clinicians, physicians, and research scientists who wish to gain insight into the mostrecent advances in this rapidly growing field.
The exosome revolution may well be the greatest advance in physiology and medicine sinceantibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is amajor breakthrough in our understanding of how cells function. Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Lawrence R. Edelstein, Ph.D. is a neuroscientist and pharmaceutical industry consultant with research interests in multisensory convergence/integration (claustrum) and intercellular communication (exosomes, telocytes). His interest in exosomes was fueled by a theme issue he guest-edited with John Smythies and Denis Noble entitled "Epigenetic information-processing mechanisms in the brain? (2014; https://royalsocietypublishing.org/toc/rstb/369/1652). That undertaking proved to be the impetus for a series of peer-reviewed articles in which he and his colleagues theorized as to the whys and wherefores of the multifunctional roles played by seemingly omnipresent and phyla-agnostic exosomes. In addition, Dr. Edelstein is co-editor (along with John Smythies and Vilayanur S. Ramachandran, M.B.B.S., Ph.D., Hon. F.R.C.P.) of the book Claustrum - Structural, Functional and Clinical Neuroscience (2014; www.elsevier.com/books/the-claustrum/smythies/978-0-12-404566-8).
Peter J. Quesenberry, M.D., is the Paul Calabresi Professor of Oncology at The Warren Alpert Medical School of Brown University. He received his medical degree from the University of Virginia, completed residency at University Hospital and Boston City Hospital in Boston, MA, and completed a Hematology/Oncology Fellowship at St. Elizabeth's Hospital.
Professor Quesenberry is a leading investigator in stem cell biology and extracellular vesicle research. He was President of the International Society of Hematology, editor of the journal Experimental Hematology from 1990-1998 and the leukocyte editor for the Year Book of Hematology from 1987-1998. More recently he is a co-editor-in-chief for the Journal of Extracellular Vesicles.
Inhaltsangabe
1. Exosome Basic Mechanisms 2. Methods for exosome isolation and characterization 3. Exosomes, microvesicles, and their friends in solid tumors 4. Hematologic malignancies: the exosome contribution in tumor progression 5. Physiological and pathological functions of prostasomes: From basic research to clinical application 6. The function and therapeutic use of exosomes in bacterial infections 7. Emerging therapeutic roles of exosomes in HIV-1 infection 8. Extracellular vesicles in parasitic disease 9. Exosomes as intercellular communication messengers for cardiovascular and cerebrovascular diseases 10. Exosomes in Cutaneous Biology and Dermatologic Disease 11. Exosomes in Nephrology 12. Extracellular vesicles in neurodegenerative disorders 13. Extracellular vesicles in fibrotic diseases: New applications for fibrosis diagnosis and treatment 14. Mechanisms of exosome-mediated immune cell crosstalk in inflammation and disease 15. Exosomes in Metabolic Syndrome 16. Potential Role of Exosomes In Reproductive Medicine And Pregnancy 17. Exosomes in Respiratory Disease 18. Exosomes in Retinal Diseases 19. MSC-exosomes in regenerative medicine 20. The potential of exosomes as theragnostics in various clinical situations 21. Exosomes, Gemmules, Pangenesis and Darwin
1. Exosome Basic Mechanisms 2. Methods for exosome isolation and characterization 3. Exosomes, microvesicles, and their friends in solid tumors 4. Hematologic malignancies: the exosome contribution in tumor progression 5. Physiological and pathological functions of prostasomes: From basic research to clinical application 6. The function and therapeutic use of exosomes in bacterial infections 7. Emerging therapeutic roles of exosomes in HIV-1 infection 8. Extracellular vesicles in parasitic disease 9. Exosomes as intercellular communication messengers for cardiovascular and cerebrovascular diseases 10. Exosomes in Cutaneous Biology and Dermatologic Disease 11. Exosomes in Nephrology 12. Extracellular vesicles in neurodegenerative disorders 13. Extracellular vesicles in fibrotic diseases: New applications for fibrosis diagnosis and treatment 14. Mechanisms of exosome-mediated immune cell crosstalk in inflammation and disease 15. Exosomes in Metabolic Syndrome 16. Potential Role of Exosomes In Reproductive Medicine And Pregnancy 17. Exosomes in Respiratory Disease 18. Exosomes in Retinal Diseases 19. MSC-exosomes in regenerative medicine 20. The potential of exosomes as theragnostics in various clinical situations 21. Exosomes, Gemmules, Pangenesis and Darwin
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