Experimental models of minimal cell - D'Aguanno, Erica
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The goal of synthetic biology is to construct cell-like systems with minimal complexity to understand the fundamental features and structures of biology, e.g. the origin of life, and for potential application in biotechnology. This study combines bottom-up approach, liposome technology and biomolecular systems to figure out how primitive cells originated from the matter. The results suggest that there is a spontaneous pathway for concentrating solute molecules in the vesicle water pool. The lipid membrane is not any longer only a physical protection, but it plays an active role recruiting molecules inside its lumen.…mehr

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Produktbeschreibung
The goal of synthetic biology is to construct cell-like systems with minimal complexity to understand the fundamental features and structures of biology, e.g. the origin of life, and for potential application in biotechnology. This study combines bottom-up approach, liposome technology and biomolecular systems to figure out how primitive cells originated from the matter. The results suggest that there is a spontaneous pathway for concentrating solute molecules in the vesicle water pool. The lipid membrane is not any longer only a physical protection, but it plays an active role recruiting molecules inside its lumen.
Autorenporträt
Dr. Erica D'Aguanno studies the origin of life since 2008, when she joined the Professor Pier Luigi Luisi's group in the university of Roma Tre. Her published works deal with the design of minimal cell using a semi-synthetic approach. From 2011 to 2015 she worked in the group of Professor Alfred Fahr in Jena, where she obtained her PhD.