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Written for biomedical researchers, this manual on the experimental surgery of rats summarizes a series of techniques that have been applied at the Bone Biology Laboratories, School of Medicine, Rosario National University, Argentina. Stopping short of an exhaustive analysis of the techniques, the manual describes the basis of each surgical technique, the necessary materials including catheters, precautions to consider, the methodology to apply, and the possible results to be obtained. The descriptions of each technique appear with diagrams and pictures.