Exploitation of Therapeutic Activities of Vernonia Amigdalina
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A wound is a crack in the continuity of tissue from wildness or trauma. A wound has to be cared for to avoid excessive loss of physiological fluids and bacterial infection or sepsis. The use of phytomedicine has increased since years till date which has been supported by a lot of evidence to show the immense potential therapeutic values. Vernonia amygdalina is a locally available phytomedicinal shrub with wound healing activity. The objectives of the research work were to review wounds, and Vernonia amygdalina, extract an active ingredient, formulate ointments with the extract, evaluate the wo...
A wound is a crack in the continuity of tissue from wildness or trauma. A wound has to be cared for to avoid excessive loss of physiological fluids and bacterial infection or sepsis. The use of phytomedicine has increased since years till date which has been supported by a lot of evidence to show the immense potential therapeutic values. Vernonia amygdalina is a locally available phytomedicinal shrub with wound healing activity. The objectives of the research work were to review wounds, and Vernonia amygdalina, extract an active ingredient, formulate ointments with the extract, evaluate the wound healing property, and compare to a standard antibiotic. The wound healing effect was conducted using the excision wound healing model in Wistar rats. Different percentages of the extract were formulated. The result showed that the standard antibiotic was equipotent with 20 % ointment . There was a progressive decrease in the wound area with time in all the ointment signifying an efficiency of the formulation in the healing of a wound. Therefore, Vernonia amygdalina has intrinsic wound healing properties at any given concentration.
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