Exploration of fermentation strategies for triterpenoid production in Saccharomyces cerevisiae

Exploration of fermentation strategies for triterpenoid production in Saccharomyces cerevisiae

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Triterpenoids are plant secondary metabolites with wide application fields. Their production in microbial cell factories is a more advantageous alternative to the existing processes. This work focusses on gaining insights into cell performance for an optimal process design. For this, a novel analytical method and a strategy to overcome limitations caused by intracellular product accumulation, and for simplification of the downstream process were evaluated.