Explore The Role of Methylation in Cancer Epigenetics - Sharma, Shivi;chaurasia, Aayushi;Panta, Rakshya
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Epigenetics is a dazzling part of Biotechnology. Using Bioniformatics tools we can explore cancer epigenetics which can give better results for mankind. In cancer cells, CpG islands preceding tumor suppressor gene promoters are often hypermethylated which result in silencing of those genes. Various transcription factors are selected and bioinformatics tools can be used to find methylation sites. The methylation of DNA sequences leads to the modification of histones with the help of MDB proteins leading to formation of heterochromatin. All these events aid in causing cancer.

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Produktbeschreibung
Epigenetics is a dazzling part of Biotechnology. Using Bioniformatics tools we can explore cancer epigenetics which can give better results for mankind. In cancer cells, CpG islands preceding tumor suppressor gene promoters are often hypermethylated which result in silencing of those genes. Various transcription factors are selected and bioinformatics tools can be used to find methylation sites. The methylation of DNA sequences leads to the modification of histones with the help of MDB proteins leading to formation of heterochromatin. All these events aid in causing cancer.
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Autorenporträt
Frau Shivi Sharma, Assistenzprofessorin (Fakultät) am Hindustan College of Science and Technology, Mathura (angegliedert an die Dr. APJ Abdul Kalam Technical University, Lucknow, U.P., Indien) hat unter ihrer Leitung Projektarbeiten von B.Tech-Studenten (Frau Rakshya, Aayushi & Deeksha) betreut. Zuvor hatten Shivi et al. erstmals in Indien die Stammesformatik eingeführt.