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Main description:
The proliferation of extracellular matrix family members reflects the progress in cloning techniques in recent years. PCR, in particular, has made a tremendous difference. These technical advances are covered in this volume.
Review quote:
Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each
…mehr

Produktbeschreibung
Main description:
The proliferation of extracellular matrix family members reflects the progress in cloning techniques in recent years. PCR, in particular, has made a tremendous difference. These technical advances are covered in this volume.

Review quote:
Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY

Table of contents:
Extracellular Matrix Proteins:
N. Fukai, S.S. Apte, and B.R. Olsen, Nonfibrillar Collagens.

L.Y. Sakai and D.R. Keene, Fibrillin: Monomers and Microfibrils.

S. Schenk and R. Chiquet-Ehrisman, Tenascins.

P. Bornstein and E.H. Sage, Thrombospondins.

U.M. Wewer and E. Engvall, Laminins.

R.U. Margolis and R.K. Margolis, Aggrecan(Versican(Neurocan Family of Proteoglycans.

Receptors:
R.H. Kramer, Characterization of Laminin-Binding Integrins.

S.A. Santoro, M.M. Zutter, J.E. Wu, W.D. Staatz, E.U.M. Saelman, and P.J. Keely, Analysis of Collagen Receptors.

R.J. Faull, X. Du, and M.H. Ginsberg, Receptors on Platelets.

I. Stamenkovic and A. Aruffo, Hyaluronic Acid Receptors.

Extracellular Matrix Components That Do Not Self-Assemble:
A.C. Rapraeger, S. Guimond, A. Krufka, and B.B. Olwin, Regulation by Heparan Sulfate in Fibroblast Growth Factor Signaling.

J.R. Harper, R.C. Spiro, W.A. Gaarde, R.N. Tamura, M.D. Pierschbacher, N.A. Noble, K.K. Stecker, and W.A. Border, Role of Transforming Growth Factor ( and Decorin in Controlling Fibrosis.

Extracellular Matrix in Invertebrates:
J.E. Schwarzbauer, F. Musset-Bilal, and C.S. Ryan, Extracellular Calcium-Binding Protein SPARC/Osteonectin in Caenorhabditis elegans.

L.I. Fessler, R.E. Nelson, and J.H. Fessler, Drosophila Extracellular Matrix.

Modern Methods in Extracellular Matrix Research:
F.G. Giancotti, L. Spinardi, F. Mainiero,and R. Sanders, Expression of Heterologous Integrin Genes in Cultured Eukaryotic Cells.

B.G. Hoffstrom and E.A. Wayner, Immunohistochemical Techniques in the Study of Extracellular Matrix and Its Receptors.

E. Koivunen, B. Wang, C.D. Dickinson, and E. Ruoslahti, Peptides in Cell Adhesion Research.

K.T. ONeil, W.F. DeGrado, S.A. Mousa, N. Ramachandran, and R.H. Hoess, Identification of Recognition Sequences of Adhesion Molecules Using Phage Display Technology.

E.L. George and R.O.Hynes, Gene Targeting and Generation of Mutant Mice for Studies of Cell(Extracellular Matrix Interactions.

R. Pytela, S. Suzuki, J. Breuss, D.J. Erle, and D. Sheppard, Polymerase Chain Reaction Cloning with Degenerate Primers: Homology-Based Identification of Adhesion Molecules.

M.J. Williams and I.D. Campbell, Solution Structures of Modular Proteins by Nuclear Magnetic Resonance.

J. Engel, Electron Microscopy of Extracellular Matrix Components.

P.D. Yurchenco and J.J. ORear, Basement Membrane Assembly.

J.A. McDonald, Extracellular Matrix Assembly.

Use of Extracellular Matrix:
R.J. Blaschke, A.R. Howlett, P.-Y. Desprez, O.W. Petersen, and M.J. Bissell, Cell Differentiation by Extracellular Matrix Components.

J.F. Tschopp, W.S. Craig, J. Tolley, J. Blevitt, C. Mazur, and M.D. Pierschbacher, Therapeutic Application of Matrix Biology.
Author Index.
Subject Index.