This book includes the possibility of isolating and extracting compounds secondary metabolism of isolate a dermatophytes Trichophyton rubrum and evaluate its ability to produce bioactive metabolites that tested as antibacterial agent, anti-oxidant activity and cytotoxicity activity, The optimization of growth conditions and production of secondary metabolites by the isolated dermatophyte On modified Media and used the Fourier Transform Infrared spectrophotometer (FTIR) analysis the present study established the ability of a dermatophyte , T. rubrum to produce antibiotic-like substances, especially the Sulfones which it is extracted and diagnosis at the first time from T. rubrum .