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Over the past few decades, health care industries and medical practitioners faced a lot of obstacles to diagnosing medical-related problems due to inadequate technology and availability of equipment. In the present era, computer science technologies such as IoT, Cloud Computing, Artificial Intelligence (AI) and its allied techniques, etc. are using rapidly for medical disease diagnosis, identifications and further treatments, especially in Ophthalmology domain. In Ophthalmology, visual impairment is increasing manifolds and is likely to reach an epidemic rise globally in the next few decades. Some of the hazardous diseases which are the main reason for visual impairment and sight loss in human beings are DR, AMD, DME, CNV, GL, Cataract, Myopia, Astigmatism and many more to name. Amongst them, some diseases such as CNV, DME, etc. are the severe form of AMD and DR which are life-threatening ones. These diseases are growing exponentially and majorly impact the elderly group and working professionals.