Here we report, the first direct synthesis of beta-CD/gypsum (beta.Ca-H), highly ordered functional material, simply by using beta-Cyclodextrin and calcium sulfate. The hybrid material is distinctively aligned which reveals a drastic change in chemo-physical properties. Optical switching of a Multi Responsive Solvatofluorochromic Dye and Dye/beta-CD Inclusion Complex were also investigated. Dye/beta-CD inclusion complex molecular rearrangements by isomerozation transformations were also observed and investigated in detail.