Patrick J. Morrison / Shirley V. Hodgson / Neva E. Haites (eds.)

Familial Breast and Ovarian Cancer

Genetics, Screening and Management
Herausgeber: Haites, Neva E.; Morrison, Patrick J.; Hodgson, Shirley V.

• Broschiertes Buch

Produktbeschreibung

This publication surveys the profound and far-reaching ramifications that have arisen from the very significant advances in understanding the genetic basis of familial breast and ovarian cancer. Written by international experts from Europe and North America, this book provides the busy clinician with a contemporary and wide-ranging guide to the latest developments in diagnosis, genetics, screening, prevention, and management. In addition, the volume discusses ethical and insurance issues, distinct cultural differences in breast cancer and use of recently devised cancer genetics clinics. The different referral criteria and patterns to these clinics are detailed.

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Produktdetails

• Verlag: Cambridge University Press
• Seitenzahl: 420
• Erscheinungstermin: 20. Mai 2005
• Englisch
• Abmessung: 244mm x 170mm x 23mm
• Gewicht: 721g
• ISBN-13: 9780521017770
• ISBN-10: 0521017777
• Artikelnr.: 21795490

Inhaltsangabe

Part I. Molecular Biology and Natural History: 1. Introduction Patrick
Morrison, Shirley Hodgson and Neva Haites; 2. Overview of clinical genetics
of breast cancer Neva Haites and Helen Gregory; 3. Cowden syndrome and
related disorders Charis Eng; 4. Overview of clinical genetics of ovarian
cancer Pierre Chappuis and Will Foulkes; 5. Ovarian cancer as part of HNPCC
and other hereditary colon cancer syndromes Hans Vasen and M. A. Nooy; 6.
Natural history of hereditary breast cancer Dominique Stoppa-Lyonnet, Will
Foulkes and Pierre Chappuis; 7. Pathology of the breast and ovary in
mutation carriers Sunil Lakhani and Adrienne M. Flanagan; 8. Risk
estimation for familial breast and ovarian cancer Jenny Chang-Claude and
Heiko Becher; Part II. Screening: 9. Experience of setting up a cancer
genetics service Jonathon Gray; 10. Referral criteria for cancer genetics
clinics Diana Eccles; 11. Service aspects of cancer genetic clinics Neva
Haites and Shirley Hodgson; 12. Cultural and education aspects influencing
development of cancer genetics services in different European countries
Shirley Hodgson; 13. Screening, detection and survival patterns of breast
and other cancers in high risk families Pål Møller and Michael Steel; 14.
Screening for familial ovarian cancer Barnaby Rufford, Usha Menon and Ian
Jacobs; Part III. Management: 15. Management of BRCA 1/2 mutation carriers
Pierre Chappuis and Will Foulkes; 16. Management of ovarian cancer Dirk
Brinkman and Ian Jacobs; 17. Prophylactic mastectomy in mutation carriers
Gareth Evans, Fiona Lalloo and Andrew Balidam; 18. Psychosocial aspects of
genetic counselling Steven Sutton and Alison Bish; 19. BRCA 1 and 2
testing: uptake and its measurement Lucy Brooks and Gareth Evans; 20.
Ethical aspects Patrick Morrison and Michael Steel; 21. Gene therapy of
breast and ovarian cancer Richard Kennedy and Patrick Johnston; 22. Future
directions Patrick Morrison, Shirley Hodgson and Neva Haites.